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CbzNH-PEG3-CH2CH2NH2

  • CAS No. 863973-20-0

  • Cat. No. CS-0459244
  • Purity≥98%
  • MDL No.MFCD28155474

*For research and further manufacturing use only, not for direct human use.

CbzNH-PEG3-CH2CH2NH2|CS-0459244

Structure of 863973-20-0

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General Information

  • CAS No. 863973-20-0
  • Cat. No. CS-0459244
  • Purity ≥98%
  • MDL No. MFCD28155474
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₆N₂O₅
  • Molecular Weight 326.39
  • Synonym(s) None
  • SMILES NCCOCCOCCOCCNC(=O)OCC1=CC=CC=C1

Description

CbzNH-PEG3-CH2CH2NH2 features a carbamoyl-protected amine terminus linked to a triethylene glycol spacer and a primary amine handle. This bifunctional scaffold enables site-specific conjugation in bioconjugation workflows, combining the stability of the Cbz group with the solubility and flexibility of PEG3.

Application

CbzNH-PEG3-CH2CH2NH2 serves as a versatile bifunctional linker for peptide and biomolecule conjugation, combining the stability of a Cbz-protected amine with a three-unit PEG spacer and a terminal primary amine. The PEG chain enhances solubility and reduces aggregation, while the terminal amine enables facile coupling to carboxyl-containing molecules or activated esters. Bench-stable and compatible with standard synthetic workflows, it facilitates efficient conjugation in solid-phase and solution-phase syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   92.04
  • LogP   0.9213
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   13

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