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Structure of 86393-33-1
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.
Fluoroquinolonic acid serves as a key building block in the synthesis of fluoroquinolone antibiotics, enabling efficient construction of the core quinolone scaffold. Its fluorinated aromatic ring system exhibits enhanced stability and predictable reactivity in standard condensation and cyclization protocols. The carboxylic acid functionality facilitates straightforward derivatization and purification, making it well-suited for iterative medicinal chemistry campaigns and scale-up processes in pharmaceutical R&D.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H412
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Precautionary Statements : P264-P270-P273-P330-P501
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Lot numbers can be found on the outside label of a product: