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CS-W001157 4
Total: USD 88.00

(2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

  • CAS No. 86392-74-7

  • Cat. No. CS-0459242
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0459242

Structure of 86392-74-7

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General Information

  • CAS No. 86392-74-7
  • Cat. No. CS-0459242
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆N₄O₄
  • Molecular Weight 280.28
  • Synonym(s) 2-AMINO-4-METHOXY-7-(BETA-D-2-DEOXYRIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
  • SMILES O[C@H]1C[C@H](N2C=CC3=C(N=C(N)N=C32)OC)O[C@@H]1CO

Synthesis

  • Route1
    • null|null
      124-41-4
    • null|null
      104291-20-5
    • ~92%
    • (2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0459242
      86392-74-7

    References

    • Ramasamy; Imamura; Robins; Revankar Tetrahedron Letters, 1987 , vol. 28, # 43 p. 5107 - 5110
  • Route2
    • null|null
      915286-72-5
    • null|null
      67-56-1
    • ~93%
    • (2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0459242
      86392-74-7

    References

    • Jain, Moti L.; Bruice, Thomas C. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 21 p. 7333 - 7346
  • Route3

    References

    • Jain, Moti L.; Bruice, Thomas C. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 21 p. 7333 - 7346

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   126.51
  • LogP   -0.3165
  • H_Acceptors   7
  • H_Donors   4
  • Rotatable_Bonds   3

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