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Structure of 863111-48-2
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This trifluoromethyl-substituted aniline features a bromo and chloro group at the 2- and 5-positions, enabling selective cross-coupling reactions. The electron-deficient aryl core enhances reactivity in palladium-catalyzed transformations, while the bench-stable, moisture-tolerant structure simplifies handling in synthetic workflows.
2-Bromo-5-chloro-4-(trifluoromethyl)aniline serves as a versatile building block for constructing substituted heterocycles and bioactive scaffolds. Its orthogonal halogen functionality enables sequential cross-coupling reactions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The compound exhibits good bench stability and facilitates efficient purification via crystallization or column chromatography, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: