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CS-W001157 4
Total: USD 88.00

3,5-Dichloro-4-(trifluoromethyl)benzenamine

  • CAS No. 496052-55-2

  • Cat. No. CS-W020198
  • Purity≥97%
  • MDL No.MFCD03788476

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloro-4-(trifluoromethyl)benzenamine|CS-W020198

Structure of 496052-55-2

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General Information

  • CAS No. 496052-55-2
  • Cat. No. CS-W020198
  • Purity ≥97%
  • MDL No. MFCD03788476
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄Cl₂F₃N
  • Molecular Weight 230.01
  • Synonym(s) 3,5-Dichloro-4-(trifluoromethyl)aniline
  • SMILES NC1=CC(Cl)=C(C(F)(F)F)C(Cl)=C1

Description

3,5-Dichloro-4-(trifluoromethyl)benzenamine features a trifluoromethyl group flanked by two chlorine substituents, delivering enhanced electron-withdrawing character and metabolic stability. This aryl amine integrates readily into pharmaceutical intermediates and agrochemical scaffolds, offering improved solubility and reactivity under standard conditions.

Application

3,5-Dichloro-4-(trifluoromethyl)benzenamine serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling direct incorporation of electron-withdrawing trifluoromethyl and chlorine substituents into heterocyclic frameworks. Its stability under standard reaction conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient construction of complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.5944
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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