5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Name: 5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 862729-13-3
Cat. No. CS-0045873
Purity≥98%
MDL No.MFCD21603870

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine|CS-0045873

Structure of 862729-13-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine features a sterically accessible pyrrolopyrimidine core with a reactive iodine at C5 and a methyl group at C7, enabling efficient cross-coupling transformations. The electron-deficient heterocycle pairs effectively with palladium catalysts, delivering stable arylated derivatives under standard conditions. This scaffold serves as a key building block in the synthesis of kinase inhibitors and nucleoside analogs.

Application

5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine serves as a versatile building block for medicinal chemistry and catalytic cross-coupling reactions. The iodide group enables reliable Suzuki-Miyaura and Buchwald-Hartwig couplings, while the pyrrolo[2,3-d]pyrimidine core provides a stable, electron-deficient scaffold commonly found in kinase inhibitors and antiviral agents. Bench-stable and readily purified by chromatography, it functions effectively in modular synthesis of heterocyclic APIs and functionalized nucleosides.

General Information

CAS No. 862729-13-3
Cat. No. CS-0045873
Purity ≥98%
MDL No. MFCD21603870
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇IN₄
Molecular Weight 274.06
Synonym(s) 5-iodo-7-methylpyrrolo[2,3-d]pyrimidin-4-amine
SMILES CN1C=C(I)C2=C1N=CN=C2N

Computational Chemistry Data

TPSA 56.73
LogP 1.1551
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

862729-13-3 sigma862729-13-3 manufacturer862729-13-3 price862729-13-3 structure862729-13-3 SDSbuy 862729-13-3862729-13-3 supplier862729-13-3 uses862729-13-3 molecular weightprice of 862729-13-3862729-13-3 chemical name formula of 862729-13-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS No. 862729-13-3

Recommended Products