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CS-W001157 4
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Quinolin-2-ylmethanamine hydrochloride

  • CAS No. 861036-67-1

  • Cat. No. CS-0456360
  • Purity≥98%
  • MDL No.MFCD09966142

*For research and further manufacturing use only, not for direct human use.

Quinolin-2-ylmethanamine hydrochloride|CS-0456360

Structure of 861036-67-1

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General Information

  • CAS No. 861036-67-1
  • Cat. No. CS-0456360
  • Purity ≥98%
  • MDL No. MFCD09966142
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁ClN₂
  • Molecular Weight 194.66
  • Synonym(s) (2-Quinolyl)methylamine hydrochloride
  • SMILES NCC1=NC2=CC=CC=C2C=C1.Cl

Description

Quinolin-2-ylmethanamine hydrochloride features a quinoline scaffold with a primary amine tethered to a methylene linker, delivering enhanced solubility and stability. This bench-stable derivative enables direct incorporation into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds, where the nitrogen-rich heterocycle facilitates key hydrogen bonding interactions.

Application

Quinolin-2-ylmethanamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard amine coupling and functionalization reactions. The hydrochloride salt enhances bench stability and solubility, facilitating purification and handling in multi-step syntheses. Its reactivity supports diverse transformations including reductive amination, acylation, and heterocycle formation, making it well-suited for the construction of biologically active compounds and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.1153
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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