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CS-W001157 4
Total: USD 88.00

4-Boc-2-cyanopiperidine

  • CAS No. 859518-35-7

  • Cat. No. CS-0002019
  • Molecule weight211.26
  • Purity≥95%
  • MDL No.MFCD09991479

*For research and further manufacturing use only, not for direct human use.

4-Boc-2-cyanopiperidine|CS-0002019

Structure of 859518-35-7

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General Information

  • CAS No. 859518-35-7
  • Cat. No. CS-0002019
  • Purity ≥95%
  • MDL No. MFCD09991479
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇N₃O₂
  • Molecular Weight 211.26
  • Synonym(s) tert-Butyl 3-cyanopiperazine-1-carboxylate
  • SMILES N#CC(NCC1)CN1C(OC(C)(C)C)=O

Description

4-Boc-2-cyanopiperidine delivers a protected piperidine scaffold bearing a nitrile group at the 2-position, enabling direct incorporation into complex molecular architectures. The Boc moiety ensures stability and facilitates selective deprotection under mild acidic conditions. This bifunctional intermediate supports efficient synthesis of bioactive compounds through conjugation strategies.

Application

4-Boc-2-cyanopiperidine serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted piperidine scaffolds. The Boc group provides stable protection of the nitrogen, while the nitrile moiety offers a reliable handle for downstream functionalization via hydrolysis, reduction, or nucleophilic addition. Its bench-stable nature and compatibility with standard coupling and cyclization protocols make it ideal for modular synthesis of bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.36
  • LogP   0.71888
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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