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CS-W001157 4
Total: USD 88.00

2',3',5',6'-Tetrahydrospiro[indoline-3,4'-pyran]

  • CAS No. 859164-46-8

  • Cat. No. CS-W015934
  • Molecule weight189.26
  • Purity≥95%
  • MDL No.MFCD15146321

*For research and further manufacturing use only, not for direct human use.

2',3',5',6'-Tetrahydrospiro[indoline-3,4'-pyran]|CS-W015934

Structure of 859164-46-8

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General Information

  • CAS No. 859164-46-8
  • Cat. No. CS-W015934
  • Purity ≥95%
  • MDL No. MFCD15146321
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO
  • Molecular Weight 189.26
  • Synonym(s) 1,2,2',3',5',6'-HEXAHYDROSPIRO[INDOLE-3,4'-PYRAN]
  • SMILES C12=C(NCC23CCOCC3)C=CC=C1

Synthesis

  • Route1
    • 4-(2-Fluorophenyl)tetrahydro-2h-pyran-4-carbonitrile|CS-0269523
      859164-45-7
    • ~44%
    • 2',3',5',6'-Tetrahydrospiro[indoline-3,4'-pyran]|CS-W015934
      859164-46-8

    References

    • ELI LILLY AND COMPANY Patent: WO2005/66126 A1, 2005 ; Location in patent: Page/Page column 44 ; WO 2005/066126 A1
  • Route2

    References

    • Liu, Kevin G.; Lo, Jennifer R.; Robichaud, Albert J. Tetrahedron, 2010 , vol. 66, # 3 p. 573 - 577

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.1603
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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