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CS-W001157 4
Total: USD 88.00

4-Bromo-2-fluoro-6-methoxybenzaldehyde

  • CAS No. 856767-09-4

  • Cat. No. CS-W019222
  • Purity≥98%
  • MDL No.MFCD22543644

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-fluoro-6-methoxybenzaldehyde|CS-W019222

Structure of 856767-09-4

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General Information

  • CAS No. 856767-09-4
  • Cat. No. CS-W019222
  • Purity ≥98%
  • MDL No. MFCD22543644
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO₂
  • Molecular Weight 233.03
  • Synonym(s) None
  • SMILES O=CC1=C(OC)C=C(Br)C=C1F

Description

4-Bromo-2-fluoro-6-methoxybenzaldehyde features a trifunctional aromatic core with bromo, fluoro, and methoxy substituents positioned ortho and para to the aldehyde group. This electron-deficient benzaldehyde integrates readily into cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles and pharmaceutical building blocks.

Application

4-Bromo-2-fluoro-6-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted aromatic scaffolds. Its orthogonal reactivity profile—combining electrophilic bromine, fluorine, and methoxy groups with a readily functionalized aldehyde—facilitates diverse transformations including Suzuki-Miyaura coupling, nucleophilic addition, and condensation reactions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for multi-step syntheses and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.4093
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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