(1-Isopropyl-1H-pyrazol-5-yl)boronic acid

Name: (1-Isopropyl-1H-pyrazol-5-yl)boronic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 839714-33-9
Cat. No. CS-B1110
Purity≥95%
MDL No.MFCD11098002

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(1-Isopropyl-1H-pyrazol-5-yl)boronic acid|CS-B1110

Structure of 839714-33-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 839714-33-9
Cat. No. CS-B1110
Purity ≥95%
MDL No. MFCD11098002
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₁BN₂O₂
Molecular Weight 153.97
Synonym(s) B-[1-(1-methylethyl)-1H-pyrazol-5-yl]-Boronic acid
SMILES CC(N1N=CC=C1B(O)O)C

Description

This boronate moiety integrates a sterically hindered pyrazole scaffold, enhancing stability and solubility in polar solvents. The isopropyl group imparts favorable handling characteristics, enabling reliable use in Suzuki-Miyaura cross-coupling reactions under standard conditions.

Application

(1-Isopropyl-1H-pyrazol-5-yl)boronic acid serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyrazole core provides enhanced stability and solubility compared to simpler arylboronic acids, while the isopropyl substituent improves bench handling and reduces protodeboronation. The compound exhibits good functional group tolerance and facilitates the synthesis of substituted heterocycles relevant to medicinal chemistry and agrochemical development.

Synthesis

Route1
- In-stock
  
  18952-87-9
- ~59%
- In-stock
  
  839714-33-9
References
- Teegarden, Bradley R.; Li, Hongmei; Jayakumar, Honnappa; Strah-Pleynet, Sonja; Dosa, Peter I.; Selaya, Susan D.; Kato, Naomi; Elwell, Katie H.; Davidson, Jarrod; Cheng, Karen; Saldana, Hazel; Frazer, John M.; Whelan, Kevin; Foster, Jonathan; Espitia, Stephan; Webb, Robert R.; Beeley, Nigel R. A.; Thomsen, William; Morairty, Stephen R.; Kilduff, Thomas S.; Al-Shamma, Hussien A. Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 1923 - 1936
Route2
- In-stock
  
  688-74-4
- In-stock
  
  18952-87-9
- ~%
- In-stock
  
  839714-33-9
References
- Roche Palo Alto LLC Patent: US2009/170873 A1, 2009 ; Location in patent: Page/Page column 48 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 58.28
LogP -0.8562
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

839714-33-9 sigma839714-33-9 manufacturer839714-33-9 price839714-33-9 structure839714-33-9 SDSbuy 839714-33-9839714-33-9 supplier839714-33-9 uses839714-33-9 molecular weightprice of 839714-33-9839714-33-9 chemical name formula of 839714-33-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(1-Isopropyl-1H-pyrazol-5-yl)boronic acid

CAS No. 839714-33-9

Recommended Products