Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

[(5-Bromopentyl)oxy](tert-butyl)dimethylsilane

  • CAS No. 85514-43-8

  • Cat. No. CS-0162405
  • Purity≥96%
  • MDL No.MFCD20261073

*For research and further manufacturing use only, not for direct human use.

[(5-Bromopentyl)oxy](tert-butyl)dimethylsilane|CS-0162405

Structure of 85514-43-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 85514-43-8
  • Cat. No. CS-0162405
  • Purity ≥96%
  • MDL No. MFCD20261073
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₅BrOSi
  • Molecular Weight 281.31
  • Synonym(s) None
  • SMILES BrCCCCCO[Si](C)(C)C(C)(C)C

Description

This silane reagent features a bromoalkyl chain tethered to a bulky tert-butyl dimethylsilyl group, enabling selective functionalization under mild conditions. The silyl moiety provides robust protection for alcohols and amines, while the (5-bromopentyl)oxy handle facilitates efficient coupling reactions in synthetic sequences. Bench-stable and moisture-tolerant, it streamlines access to complex architectures in organic synthesis and materials chemistry.

Application

[(5-Bromopentyl)oxy](tert-butyl)dimethylsilane serves as a robust silyl-protected hydroxyl synthon, enabling reliable etherification and chain extension in complex molecule synthesis. Its bromide handle facilitates nucleophilic substitution with amines, thiols, and carbon nucleophiles, while the bulky tert-butyldimethylsilyl group ensures excellent stability and selective deprotection under mild conditions. Ideal for constructing polyether scaffolds and functionalized intermediates in medicinal chemistry and natural product synthesis.

Synthesis

  • Route1
    • In-stock
      5-Bromopentan-1-ol,80%|CS-0905394
      34626-51-2
    • null|null
      18162-48-6
    • ~92%
    • In-stock
      [(5-Bromopentyl)oxy](tert-butyl)dimethylsilane|CS-0162405
      85514-43-8

    References

    • Li, Chen; Xu, Wei; Vadivel, Subramanian K.; Fan, Pusheng; Makriyannis, Alexandros Journal of Medicinal Chemistry, 2005 , vol. 48, # 20 p. 6423 - 6429
  • Route2
    • null|null
      142-68-7
    • ~%
    • In-stock
      [(5-Bromopentyl)oxy](tert-butyl)dimethylsilane|CS-0162405
      85514-43-8

    References

    • Kaiser, Florian; Schwink, Lothar; Velder, Janna; Schmalz, Hans-Guenther Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9248 - 9256
  • Route3

    References

    • Hu; Weiler Canadian Journal of Chemistry, 1994 , vol. 72, # 6 p. 1500 - 1511

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   4.5734
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   6

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 85514-43-8 sigma85514-43-8 manufacturer85514-43-8 price85514-43-8 structure85514-43-8 SDSbuy 85514-43-885514-43-8 supplier85514-43-8 uses85514-43-8 molecular weightprice of 85514-43-885514-43-8 chemical name formula of 85514-43-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label