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CS-W001157 4
Total: USD 88.00

4-Bromobutoxy-tert-butyl-dimethylsilane

  • CAS No. 89043-32-3

  • Cat. No. CS-0139732
  • Purity≥97%
  • MDL No.MFCD20259686

*For research and further manufacturing use only, not for direct human use.

4-Bromobutoxy-tert-butyl-dimethylsilane|CS-0139732

Structure of 89043-32-3

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General Information

  • CAS No. 89043-32-3
  • Cat. No. CS-0139732
  • Purity ≥97%
  • MDL No. MFCD20259686
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₃BrOSi
  • Molecular Weight 267.28
  • Synonym(s) None
  • SMILES BrCCCCO[Si](C)(C)C(C)(C)C

Description

4-Bromobutoxy-tert-butyl-dimethylsilane delivers a robust silyl-protected ether functionality with a reactive bromide handle. This bifunctional molecule enables site-specific conjugation in synthetic workflows, combining stable storage with efficient downstream transformation under standard conditions.

Application

4-Bromobutoxy-tert-butyl-dimethylsilane serves as a versatile protected alkoxide synthon, enabling efficient etherification and nucleophilic substitution reactions. The tert-butyldimethylsilyl (TBS) group provides excellent stability under basic conditions and mild acidic deprotection, while the 4-bromobutoxy moiety facilitates coupling with nucleophiles via SN2 pathways. This compound functions reliably in multistep synthesis, offering orthogonal protection and clean functionalization for complex molecule assembly.

Synthesis

  • Route1
    • null|null
      33036-62-3
    • null|null
      18162-48-6
    • ~79%
    • In-stock
      4-Bromobutoxy-tert-butyl-dimethylsilane|CS-0139732
      89043-32-3

    References

    • Fuerstner, Alois; Mlynarski, Jacek; Albert, Martin Journal of the American Chemical Society, 2002 , vol. 124, # 35 p. 10274 - 10275
  • Route2
    • null|null
      33036-62-3
    • null|null
      58479-61-1
    • ~81%
    • In-stock
      4-Bromobutoxy-tert-butyl-dimethylsilane|CS-0139732
      89043-32-3

    References

    • Fuerstner, Alois; Albert, Martin; Mlynarski, Jacek; Matheu, Maribel; DeClercq, Erik Journal of the American Chemical Society, 2003 , vol. 125, # 43 p. 13132 - 13142
  • Route3

    References

    • Gomez; Gellibert; Wagner; Mioskowski Tetrahedron Letters, 2000 , vol. 41, # 32 p. 6049 - 6052

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   4.1833
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

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