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CS-W001157 4
Total: USD 88.00

1-(3-Methylpyridin-2-yl)ethanone

  • CAS No. 85279-30-7

  • Cat. No. CS-0092057
  • Molecule weight135.16
  • Purity≥97%
  • MDL No.MFCD08062668

*For research and further manufacturing use only, not for direct human use.

1-(3-Methylpyridin-2-yl)ethanone|CS-0092057

Structure of 85279-30-7

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General Information

  • CAS No. 85279-30-7
  • Cat. No. CS-0092057
  • Purity ≥97%
  • MDL No. MFCD08062668
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight 135.16
  • Synonym(s) 2-Acetyl-3-methylpyridine
  • SMILES CC1=CC=CN=C1C(C)=O

Description

1-(3-Methylpyridin-2-yl)ethanone features a pyridine ring bearing a methyl group at the 3-position and an acetyl substituent at the 2-position, delivering enhanced electron-withdrawing character. This configuration supports its role as a key scaffold in medicinal chemistry, enabling efficient coupling reactions and facilitating integration into bioactive molecular frameworks under standard conditions.

Application

1-(3-Methylpyridin-2-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds via nucleophilic addition and condensation reactions. Its ketone functionality exhibits good bench stability and compatibility with standard functional group transformations, facilitating downstream derivatization. The molecule functions effectively in transition-metal-catalyzed coupling processes and provides a robust platform for constructing heterocyclic motifs relevant to pharmaceutical development.

Synthesis

  • Route1

    References

    • Organic Magnetic Resonance, , vol. 20, # 4 p. 242 - 248
  • Route2

    References

    • Organic Magnetic Resonance, , vol. 20, # 4 p. 242 - 248
  • Route3
    • In-stock
      2-Cyano-3-methylpyridine|CS-W016588
      20970-75-6
    • null|null
      74-88-4
    • ~%
    • In-stock
      1-(3-Methylpyridin-2-yl)ethanone|CS-0092057
      85279-30-7

    References

    • Organic Magnetic Resonance, , vol. 20, # 4 p. 242 - 248

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.59262
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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