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CS-W001157 4
Total: USD 88.00

m-PEG4-Amine

  • CAS No. 85030-56-4

  • Cat. No. CS-W020954
  • Purity≥95%
  • MDL No.MFCD11041099

*For research and further manufacturing use only, not for direct human use.

m-PEG4-Amine|CS-W020954

Structure of 85030-56-4

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General Information

  • CAS No. 85030-56-4
  • Cat. No. CS-W020954
  • Purity ≥95%
  • MDL No. MFCD11041099
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₁NO₄
  • Molecular Weight 207.27
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCN

Description

m-PEG4-Amine features a linear, water-soluble polyethylene glycol chain with four ethylene oxide units, terminating in a primary amine group. This functionalized linker enables site-specific conjugation in bioconjugation workflows, offering enhanced solubility and stability for peptide, protein, and oligonucleotide modifications.

Application

m-PEG4-Amine serves as a versatile bifunctional linker, enabling efficient conjugation in peptide synthesis and bioconjugation workflows. Its four-ethylene glycol units provide excellent solubility and stability in aqueous and organic media, while the primary amine facilitates straightforward coupling reactions. The molecule functions as a robust spacer in drug delivery systems and diagnostic probes, offering enhanced pharmacokinetic properties through improved hydrophilicity and reduced non-specific binding.

Synthesis

  • Route1
    • Tetraethylene glycol monomethyl ether HQ|CS-1347367
      23783-42-8
    • ~%
    • In-stock
      m-PEG4-Amine|CS-W020954
      85030-56-4

    References

    • Li, Guangtao; Bhosale, Sheshanath V.; Wang, Tianyu; Hackbarth, Steffen; Roeder, Beate; Siggel, Ulrich; Fuhrhop, Juergen-Hinrich Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10693 - 10702
  • Route2
    • null|null
      136918-14-4
    • In-stock
      m-PEG3-OH|CS-0114074
      112-35-6
    • ~%
    • In-stock
      m-PEG4-Amine|CS-W020954
      85030-56-4

    References

    • Tuchscherer, Andre; Schaarschmidt, Dieter; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich European Journal of Inorganic Chemistry, 2011 , # 28 p. 4421 - 4428
  • Route3

    References

    • Li, Guangtao; Bhosale, Sheshanath V.; Wang, Tianyu; Hackbarth, Steffen; Roeder, Beate; Siggel, Ulrich; Fuhrhop, Juergen-Hinrich Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10693 - 10702

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   62.94
  • LogP   -0.3587
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   11

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