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Structure of 850142-72-2
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6-Bromo-2-fluoropyridin-3-ol features a pyridin-3-ol core functionalized with bromo and fluoro substituents at the 6- and 2-positions, respectively. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering high reactivity in Pd-catalyzed transformations. The phenolic hydroxyl group enables further derivatization, while the fluorine atom enhances metabolic stability and modulates electronic properties. Bench-stable under standard conditions, this compound serves as a key intermediate in the synthesis of bioactive molecules and advanced pharmaceutical scaffolds.
6-Bromo-2-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C3 position via nucleophilic substitution. Its bromine and hydroxyl groups provide orthogonal reactivity for cross-coupling and derivatization, while the fluorine enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and facilitates efficient synthesis of pyridine-based scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: