Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-6-fluoropyridin-3-ol

  • CAS No. 1256822-94-2

  • Cat. No. CS-0156783
  • Purity≥97%
  • MDL No.MFCD18257625

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-fluoropyridin-3-ol|CS-0156783

Structure of 1256822-94-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1256822-94-2
  • Cat. No. CS-0156783
  • Purity ≥97%
  • MDL No. MFCD18257625
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrFNO
  • Molecular Weight 191.99
  • Synonym(s) None
  • SMILES C1=CC(=NC(=C1O)Br)F

Description

2-Bromo-6-fluoropyridin-3-ol features a pyridin-3-ol core bearing bromo and fluoro substituents at the 2- and 6-positions, respectively. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering enhanced regioselectivity in late-stage functionalization. The phenolic hydroxyl group enables direct derivatization or coordination in catalytic systems. Bench-stable under standard conditions, it serves as a key building block for pharmaceutical intermediates and agrochemicals.

Application

2-Bromo-6-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling direct Suzuki-Miyaura and Buchwald-Hartwig coupling reactions due to its orthogonal halogen reactivity. The fluorine and hydroxyl groups provide enhanced metabolic stability and hydrogen-bonding capacity, while the bromine facilitates palladium-catalyzed transformations. Bench-stable and readily purified by recrystallization, it functions efficiently in the construction of substituted pyridine scaffolds common in kinase inhibitors and CNS-targeted therapeutics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.6888
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-6-fluoropyridin-3-ol sigma2-Bromo-6-fluoropyridin-3-ol manufacturer2-Bromo-6-fluoropyridin-3-ol price2-Bromo-6-fluoropyridin-3-ol structure2-Bromo-6-fluoropyridin-3-ol SDSbuy 2-Bromo-6-fluoropyridin-3-ol2-Bromo-6-fluoropyridin-3-ol supplier2-Bromo-6-fluoropyridin-3-ol uses2-Bromo-6-fluoropyridin-3-ol molecular weightprice of 2-Bromo-6-fluoropyridin-3-ol2-Bromo-6-fluoropyridin-3-ol chemical name formula of 2-Bromo-6-fluoropyridin-3-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label