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CS-W001157 4
Total: USD 88.00

2-Hydroxy-3-nitrobenzoic acid

  • CAS No. 85-38-1

  • Cat. No. CS-0097789
  • Purity≥98%
  • MDL No.MFCD00024240

*For research and further manufacturing use only, not for direct human use.

2-Hydroxy-3-nitrobenzoic acid|CS-0097789

Structure of 85-38-1

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General Information

  • CAS No. 85-38-1
  • Cat. No. CS-0097789
  • Purity ≥98%
  • MDL No. MFCD00024240
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₅
  • Molecular Weight 183.12
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=CC([N+]([O-])=O)=C1O

Application

3-Nitrosalicylic acid serves as a versatile building block in synthetic organic chemistry, enabling access to nitroso-substituted phenolic scaffolds. Its ortho-hydroxyl and nitroso groups facilitate chelation and direct functionalization, supporting applications in ligand design and heterocycle synthesis. The compound exhibits bench stability and enables straightforward derivatization under mild conditions, making it valuable for medicinal chemistry and materials science workflows.

Synthesis

  • Route1
    • Salicylic acid, ≥99%|CS-1268363
      69-72-7
    • ~%
    • In-stock
      2-Hydroxy-3-nitrobenzoic acid|CS-0097789
      85-38-1

    References

    • Annales de Chimie (Cachan, France), , vol. <3> 10, p. 329,336, 353 Justus Liebigs Annalen der Chemie, , vol. 48, p. 65 Journal fuer Praktische Chemie (Leipzig), , vol. <1> 26, p. 397 Journal fuer Praktische Chemie (Leipzig), , vol. <1> 76, p. 453 Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, , p. 310 Annales de Chimie (Cachan, France), , vol. <3> 7, p. 225 Justus Liebigs Annalen der Chemie, , vol. 45, p. 26
  • Route2

    References

    • US6297401 B1, ;
  • Route3

    References

    • Yang, Daoshan; Fu, Hua Chemistry - A European Journal, 2010 , vol. 16, # 8 p. 2366 - 2370

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.67
  • LogP   0.9986
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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