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CS-W001157 4
Total: USD 88.00

2-Hydroxy-4-quinolinecarboxylic acid

  • CAS No. 84906-81-0

  • Cat. No. CS-0043243
  • Molecule weight189.17
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Hydroxy-4-quinolinecarboxylic acid|CS-0043243

Structure of 84906-81-0

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General Information

  • CAS No. 84906-81-0
  • Cat. No. CS-0043243
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) IFLAB-BB F1918-0080
  • SMILES O=C(C1=CC(O)=NC2=CC=CC=C12)O

Description

Phenyl formate is widely used in the palladium-catalyzed carbonylation of aryl, alkenyl and allyl halides. It is also used as a reagent for the formylation of amines.

Application

2-Hydroxy-4-quinolinecarboxylic acid serves as a versatile scaffold for medicinal chemistry and materials science, enabling efficient derivatization via its carboxylic acid and phenolic hydroxyl groups. Its inherent stability and compatibility with standard coupling reactions facilitate the synthesis of quinoline-based bioactive molecules, including kinase inhibitors and metal-chelating ligands. The compound functions as a key building block in heterocyclic library development, offering predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   70.42
  • LogP   1.6386
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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