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Structure of 84832-01-9
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Methyl 2,6-difluoro-3-nitrobenzoate features a trifunctional aromatic core with strategically positioned fluorine atoms and a nitro group, enabling selective functionalization in synthetic sequences. This electron-deficient scaffold integrates readily into cross-coupling reactions and serves as a key intermediate for bioactive molecule synthesis under standard conditions.
Methyl 2,6-difluoro-3-nitrobenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of fluorinated heterocycles and substituted aromatic systems. The ortho-fluorine substituents facilitate directed metallation and subsequent functionalization, while the nitro group acts as a strong electron-withdrawing handle for nucleophilic substitution or reduction to an amine intermediate. Bench-stable and readily purified by column chromatography, it supports scalable transformations in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: