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Structure of 846048-15-5
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This brominated pyridine derivative features a methyl ester and carboxylic acid at the 1- and 3-positions, respectively, with a bromine substituent at C5. The electron-deficient dihydropyridine core enables efficient coupling in cross-coupling protocols. Bench-stable and compatible with standard synthetic conditions, it serves as a key building block for bioactive heterocycles.
5-Bromo-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its bromo and carboxylic acid functionalities offer orthogonal reactivity for sequential derivatization, while the methyl group enhances stability and modulates electronic properties. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating integration into medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319-H315-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: