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CS-W001157 4
Total: USD 88.00

3-Fluoro-5-iodobromobenzene

  • CAS No. 845866-85-5

  • Cat. No. CS-W021920
  • Purity≥98%
  • MDL No.MFCD06657969

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-iodobromobenzene|CS-W021920

Structure of 845866-85-5

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General Information

  • CAS No. 845866-85-5
  • Cat. No. CS-W021920
  • Purity ≥98%
  • MDL No. MFCD06657969
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrFI
  • Molecular Weight 300.90
  • Synonym(s) Benzene, 1-bromo-3-fluoro-5-iodo-
  • SMILES BrC1=CC(=CC(=C1)I)F

Description

3-Fluoro-5-iodobromobenzene is a trifunctional aryl halide featuring fluorine, iodine, and bromine substituents at meta and para positions relative to one another. This electron-deficient scaffold enables selective cross-coupling reactions in late-stage functionalization. The molecule exhibits enhanced stability under standard handling conditions and integrates readily into transition metal-catalyzed transformations.

Application

3-Fluoro-5-iodobromobenzene serves as a versatile diaryl building block in palladium-catalyzed cross-coupling reactions, enabling efficient synthesis of functionalized biaryls and heterocyclic scaffolds. The ortho-fluoro substituent facilitates directed metallation and subsequent functionalization, while the iodide and bromide groups offer complementary reactivity for sequential coupling processes. Bench-stable and compatible with standard reaction conditions, it supports precise molecular diversification in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.1928
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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