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1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl benzenepropanoate

  • CAS No. 84379-71-5

  • Cat. No. CS-0652830
  • Molecule weight295.29
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl benzenepropanoate|CS-0652830

Structure of 84379-71-5

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General Information

  • CAS No. 84379-71-5
  • Cat. No. CS-0652830
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₃NO₄
  • Molecular Weight 295.29
  • Synonym(s) None
  • SMILES O=C(ON(C(C1=C2C=CC=C1)=O)C2=O)CCC3=CC=CC=C3

Description

This isoindolinone derivative features a benzenepropanoate side chain that enhances solubility and facilitates conjugation in synthetic workflows. The rigid, electron-deficient core enables efficient incorporation into bioactive scaffolds and functional materials.

Application

1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl benzenepropanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of isoindoline scaffolds via standard cyclization protocols. Its dual electrophilic carbonyl functionalities facilitate controlled reductive and nucleophilic transformations, while the benzenepropanoate moiety enhances solubility and simplifies purification. The compound exhibits robust bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   63.68
  • LogP   2.3736
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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