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CS-W001157 4
Total: USD 88.00

Trimethyl(phenylethynyl)silane

  • CAS No. 2170-06-1

  • Cat. No. CS-0107213
  • Purity≥97%
  • MDL No.MFCD00054860

*For research and further manufacturing use only, not for direct human use.

Trimethyl(phenylethynyl)silane|CS-0107213

Structure of 2170-06-1

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General Information

  • CAS No. 2170-06-1
  • Cat. No. CS-0107213
  • Purity ≥97%
  • MDL No. MFCD00054860
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄Si
  • Molecular Weight 174.31
  • Synonym(s) Phenylethynyltrimethylsilane
  • SMILES C[Si](C#CC1=CC=CC=C1)(C)C

Description

1-Phenyl-2-trimethylsilylacetylene is an SiMe3-substituted alkyne. It undergoes coupling with propargylic and allylic alcohols. Polymerization of 1-phenyl-2-trimethylsilylacetylene by various transition metal catalysts has been reported.1-Phenyl-2-trimethylsilylacetylene was used in the preparation of donor-stabilized Pt-2-alkyne complexes.

Application

Trimethyl(phenylethynyl)silane serves as a stable, bench-ready silyl-protected alkyne reagent that facilitates copper-catalyzed coupling reactions, enabling efficient access to substituted alkynes in multistep synthesis. Its robustness under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for constructing complex molecular architectures, including conjugated systems and heterocyclic scaffolds.

Synthesis

  • Route1
    • null|null
      16029-98-4
    • null|null
      536-74-3
    • ~87%
    • In-stock
      Trimethyl(phenylethynyl)silane|CS-0107213
      2170-06-1

    References

    • Organometallics, , vol. 30, # 9 p. 2539 - 2545
  • Route2
    • null|null
      108-86-1
    • null|null
      1066-54-2
    • ~98%
    • In-stock
      Trimethyl(phenylethynyl)silane|CS-0107213
      2170-06-1

    References

    • Advanced Synthesis and Catalysis, , vol. 348, # 15 p. 2101 - 2113
  • Route3
    • In-stock
      Iodobenzene|CS-W008603
      591-50-4
    • null|null
      1066-54-2
    • ~98%
    • In-stock
      Trimethyl(phenylethynyl)silane|CS-0107213
      2170-06-1

    References

    • WO2013/78254 A1, ; Paragraph 00511 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.9155
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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