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Boc-C14-COOH

  • CAS No. 843666-27-3

  • Cat. No. CS-0085848
  • Purity≥97%
  • MDL No.MFCD23136039

*For research and further manufacturing use only, not for direct human use.

Boc-C14-COOH|CS-0085848

Structure of 843666-27-3

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General Information

  • CAS No. 843666-27-3
  • Cat. No. CS-0085848
  • Purity ≥97%
  • MDL No. MFCD23136039
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₃₈O₄
  • Molecular Weight 342.51
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCCCCCCCCC(OC(C)(C)C)=O

Description

Boc-C14-COOH features a long-chain aliphatic backbone with a protected carboxylic acid terminus, enabling stable incorporation into lipid-based conjugates. This bench-stable derivative facilitates efficient coupling in synthetic workflows requiring hydrophobic anchors or membrane-targeting moieties.

Application

Boc-C14-COOH serves as a versatile C14-carboxylic acid building block for the synthesis of complex organic scaffolds, particularly in the construction of steroidal and polyketide-derived frameworks. The Boc-protected carboxyl group offers excellent bench stability and compatibility with standard coupling protocols, enabling straightforward amide and ester formation under mild conditions. Its long aliphatic chain provides favorable solubility characteristics and facilitates purification via chromatography or crystallization. This reagent functions reliably in multi-step syntheses requiring orthogonal protection strategies.

Synthesis

  • Route1

    References

    • NOVO NORDISK A/S Patent: WO2007/128817 A2, 2007 ; Location in patent: Page/Page column 81 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   5.8741
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   15

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