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Structure of 84355-44-2
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Methyl tetrahydro-2H-pyran-2-carboxylate serves as a versatile chiral building block in organic synthesis, featuring a protected hydroxyl-bearing heterocyclic framework. The ester functionality enables direct functionalization, while the tetrahydropyran ring provides stereochemical stability and enhanced solubility in polar aprotic media.
Methyl tetrahydro-2H-pyran-2-carboxylate serves as a versatile building block in synthetic organic chemistry, offering a stable, bench-ready enolizable ester within a saturated heterocyclic framework. Its tetrahydropyranyl (THP) protecting group provides orthogonal stability under various reaction conditions, enabling selective deprotection and functionalization. The molecule facilitates efficient C–C bond formation via nucleophilic addition to the carbonyl, and its ester functionality supports transformations such as reduction, hydrolysis, or coupling reactions. This scaffold is particularly useful in the synthesis of complex natural products and pharmaceutical intermediates due to its predictable reactivity and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: