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CS-W001157 4
Total: USD 88.00

4-Bromobutan-2-ol

  • CAS No. 6089-17-4

  • Cat. No. CS-0142519
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromobutan-2-ol|CS-0142519

Structure of 6089-17-4

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General Information

  • CAS No. 6089-17-4
  • Cat. No. CS-0142519
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉BrO
  • Molecular Weight 153.02
  • Synonym(s) 1-bromo-3-butanol
  • SMILES CC(O)CCBr

Description

4-Bromobutan-2-ol features a bromine atom at the terminal carbon and a hydroxyl group at the C2 position, creating a bifunctional scaffold ideal for nucleophilic substitution and elimination reactions. This chiral molecule integrates readily into synthetic sequences requiring stereocontrolled functionalization.

Application

4-Bromobutan-2-ol serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and functionalized aliphatic chains. Its pendant bromide and secondary alcohol groups exhibit orthogonal reactivity, facilitating sequential transformations such as nucleophilic substitution, cyclization, or protection strategies. The compound demonstrates good bench stability and is readily purified by distillation or chromatography, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      59744-08-0
    • ~74%
    • In-stock
      4-Bromobutan-2-ol|CS-0142519
      6089-17-4

    References

    • Horner, Leopold; Schmitt, Rolf-Erhard Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 189 - 212
  • Route2
    • null|null
      18826-95-4
    • ~%
    • In-stock
      4-Bromobutan-2-ol|CS-0142519
      6089-17-4

    References

    • Evans, P Andrew; Manangan, Thara Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4523 - 4528
  • Route3
    • 4-Bromobutan-2-one|CS-0162440
      28509-46-8
    • ~%
    • In-stock
      4-Bromobutan-2-ol|CS-0142519
      6089-17-4

    References

    • Searles et al. Journal of the American Chemical Society, 1957 , vol. 79, p. 952,955

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.1522
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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