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CS-W001157 4
Total: USD 88.00

(R)-(-)-2-(Methoxymethyl)pyrrolidine

  • CAS No. 84025-81-0

  • Cat. No. CS-W002305
  • Purity≥98%
  • MDL No.MFCD00066219

*For research and further manufacturing use only, not for direct human use.

(R)-(-)-2-(Methoxymethyl)pyrrolidine|CS-W002305

Structure of 84025-81-0

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General Information

  • CAS No. 84025-81-0
  • Cat. No. CS-W002305
  • Purity ≥98%
  • MDL No. MFCD00066219
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) (R)-2-(Methoxymethyl)pyrrolidine
  • SMILES COC[C@@H]1NCCC1

Description

(R)-(-)-2-(Methoxymethyl)pyrrolidine is a chiral pyrrolidine derivative featuring a methoxymethyl group at the 2-position, offering enhanced solubility and stability. This configuration enables precise stereocontrol in asymmetric synthesis, particularly useful in medicinal chemistry for constructing bioactive scaffolds.

Application

(R)-(-)-2-(Methoxymethyl)pyrrolidine serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles and bioactive scaffolds. Its pendant methoxymethyl group offers enhanced solubility and functional group tolerance, facilitating downstream transformations such as alkylation, acylation, and cyclization. The stereochemically defined pyrrolidine core provides predictable reactivity in asymmetric synthesis, while the compound exhibits excellent bench stability and ease of purification—ideal for high-throughput screening and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3848
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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