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CS-W001157 4
Total: USD 88.00

4,4'-Methylenebis(2-methylaniline)

  • CAS No. 838-88-0

  • Cat. No. CS-W013022
  • Purity≥98%
  • MDL No.MFCD00126963

*For research and further manufacturing use only, not for direct human use.

4,4'-Methylenebis(2-methylaniline)|CS-W013022

Structure of 838-88-0

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General Information

  • CAS No. 838-88-0
  • Cat. No. CS-W013022
  • Purity ≥98%
  • MDL No. MFCD00126963
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈N₂
  • Molecular Weight 226.32
  • Synonym(s) Methane, bis[4-amino-3-methylphenyl]-
  • SMILES NC1=CC=C(CC2=CC=C(C(C)=C2)N)C=C1C

Description

.

Application

4,4'-Methylenebis(2-methylaniline) serves as a key bis-arylamine building block for the synthesis of advanced polymeric materials and functionalized heterocycles. Its robust bench stability and ortho-methyl substituents enable selective functionalization in amine-directed coupling reactions. The molecule functions effectively in Ullmann-type couplings and serves as a versatile precursor in the construction of conjugated systems and pharmaceutical intermediates requiring controlled nitrogen incorporation.

Synthesis

  • Route1
    • null|null
      50-00-0
    • null|null
      95-53-4
    • ~54%
    • In-stock
      4,4'-Methylenebis(2-methylaniline)|CS-W013022
      838-88-0

    References

    • Lin, Xiao; Zhao, Yingxian; Zhang, Shengjian; Wang, Lingyun; Wang, Yi; Guo, Yanna Catalysis Communications, 2014 , vol. 45, p. 69 - 73
  • Route2
    • null|null
      50-00-0
    • null|null
      95-53-4
    • ~%
    • null|null
      27152-77-8
    • In-stock
      4,4'-Methylenebis(2-methylaniline)|CS-W013022
      838-88-0

    References

    • EP1403241 A1, ; Page 3; 4 ;
  • Route3
    • null|null
      5293-94-7
    • null|null
      95-53-4
    • ~85%
    • In-stock
      4,4'-Methylenebis(2-methylaniline)|CS-W013022
      838-88-0
    • In-stock
      N,2-Dimethylaniline|CS-0152952
      611-21-2

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1420 - 1426

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H317-H350-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.04
  • LogP   3.05864
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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