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CS-W001157 4
Total: USD 88.00

3-Bromo-2-methylbenzyl alcohol

  • CAS No. 83647-43-2

  • Cat. No. CS-W000403
  • Purity≥97%
  • MDL No.MFCD11847531

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-methylbenzyl alcohol|CS-W000403

Structure of 83647-43-2

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General Information

  • CAS No. 83647-43-2
  • Cat. No. CS-W000403
  • Purity ≥97%
  • MDL No. MFCD11847531
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BrO
  • Molecular Weight 201.06
  • Synonym(s) (3-Bromo-o-tolyl)methanol
  • SMILES CC1=C(CO)C=CC=C1Br

Description

As indicator pH 3.8 (orange) to 6.5 (dark violet)Resazurin sodium salt acts as a blue non-fluorescent dye used especially in oxidation-reduction indicator of resazurin test for bacteria. It is employed as a fluorogenic oxidation-reduction indicator in a variety of cells, yeast and eukaryotes by flow cytometry, fluorescence microscopy and high-throughput screening. Further, it is used to characterize the metabolic activity of mitochnodria. It is also used to assay L-Glutamate and to measure the aerobic biodegradation of organic matter exists in effluents. In addition to this, it acts as an indicator for cell viability in mammalian cell cultures.

Application

3-Bromo-2-methylbenzyl alcohol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzyl derivatives. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, while the benzylic alcohol offers a handle for derivatization or protection. The molecule exhibits good bench stability and compatibility with standard purification techniques, supporting its use in multi-step synthetic sequences requiring functional group tolerance and predictable reactivity.

Synthesis

  • Route1

    References

    • TAKEDA PHARMACEUTICAL COMPANY LIMITED; NEGORO, Nobuyuki; TERAO, Yoshito; MIKAMI, Satoshi; YUKAWA, Tomoya Patent: WO2010/143733 A1, 2010 ; Location in patent: Page/Page column 347-348 ; WO 2010/143733 A1
  • Route2

    References

    • Alantos Pharmaceuticals Holding, Inc. Patent: US2008/21024 A1, 2008 ; Location in patent: Page/Page column 63 ; US 20080021024 A1
  • Route3

    References

    • BASF Aktiengesellschaft Patent: US5256666 A1, 1993 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.24982
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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