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CS-W001157 4
Total: USD 88.00

2-Chloro-7-(trifluoromethyl)quinoline

  • CAS No. 83183-56-6

  • Cat. No. CS-0134704
  • Molecule weight231.60
  • Purity≥97%
  • MDL No.MFCD11557207

*For research and further manufacturing use only, not for direct human use.

2-Chloro-7-(trifluoromethyl)quinoline|CS-0134704

Structure of 83183-56-6

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General Information

  • CAS No. 83183-56-6
  • Cat. No. CS-0134704
  • Purity ≥97%
  • MDL No. MFCD11557207
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₅ClF₃N
  • Molecular Weight 231.60
  • Synonym(s) 2-chloro-7-(trifluoroMethyl) quinoline
  • SMILES FC(F)(F)C1=CC=C2C=CC(Cl)=NC2=C1

Synthesis

  • Route1
    • 7-(Trifluoromethyl)quinolin-2-ol|CS-0510007
      1011533-24-6
    • ~25%
    • 2-Chloro-7-(trifluoromethyl)quinoline|CS-0134704
      83183-56-6

    References

    • PFIZER INC.; DIDIUK, Mary; FILIPSKI, Kevin J.; GUZMAN-PEREZ, Angel; LEE, Esther C.; PFEFFERKORN, Jeffrey A.; STEVENS, Benjamin; TU, Meihua Patent: WO2013/14569 A1, 2013 ; Location in patent: Page/Page column 33-34 ; WO 2013/014569 A1
  • Route2

    References

    • PFIZER INC.; DIDIUK, Mary; FILIPSKI, Kevin J.; GUZMAN-PEREZ, Angel; LEE, Esther C.; PFEFFERKORN, Jeffrey A.; STEVENS, Benjamin; TU, Meihua Patent: WO2013/14569 A1, 2013 ; WO 2013/014569 A1
  • Route3
    • Methyl (E)-3-(2-amino-4-(trifluoromethyl)phenyl)acrylate|CS-0450163
      231296-89-2
    • ~%
    • 2-Chloro-7-(trifluoromethyl)quinoline|CS-0134704
      83183-56-6

    References

    • PFIZER INC.; DIDIUK, Mary; FILIPSKI, Kevin J.; GUZMAN-PEREZ, Angel; LEE, Esther C.; PFEFFERKORN, Jeffrey A.; STEVENS, Benjamin; TU, Meihua Patent: WO2013/14569 A1, 2013 ; WO 2013/014569 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.907
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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