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Structure of 82401-91-0
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2-(Chloromethyl)-5-methoxypyridine hydrochloride features a reactive chloromethyl group flanked by a methoxy-substituted pyridine ring, enabling efficient alkylation under mild conditions. The hydrochloride salt enhances solubility and stability in polar solvents, simplifying handling in synthetic workflows. This compound serves as a key intermediate for bioactive heterocycles and functionalized polymers.
2-(Chloromethyl)-5-methoxypyridine hydrochloride serves as a versatile electrophilic building block for pyridine-based heterocycles, enabling efficient C–C and C–heteroatom bond formation. The chloromethyl group facilitates nucleophilic substitution under mild conditions, while the methoxy substituent provides moderate electronic stabilization and enhanced solubility. Bench-stable and readily purified by recrystallization, it functions reliably in standard coupling protocols and scaffold elaboration for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: