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CS-W001157 4
Total: USD 88.00

2-Methoxyhydroquinone

  • CAS No. 824-46-4

  • Cat. No. CS-W014391
  • Purity≥98%
  • MDL No.MFCD00013971

*For research and further manufacturing use only, not for direct human use.

2-Methoxyhydroquinone|CS-W014391

Structure of 824-46-4

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General Information

  • CAS No. 824-46-4
  • Cat. No. CS-W014391
  • Purity ≥98%
  • MDL No. MFCD00013971
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₃
  • Molecular Weight 140.14
  • Synonym(s) None
  • SMILES COC1=C(O)C=CC(O)=C1

Description

2-Methoxyhydroquinone delivers a stabilized hydroxylated aromatic core with enhanced solubility and resistance to oxidation. This phenolic compound features a methoxy group at the ortho position, enabling selective reactivity in synthetic transformations. Its bench-stable nature supports reliable use in pharmaceutical intermediates and antioxidant research.

Application

2-Methoxyhydroquinone serves as a versatile phenolic building block in synthetic organic chemistry, enabling access to functionalized aromatic scaffolds through standard coupling and oxidation reactions. Its methoxy group enhances solubility and stability, while the hydroxyl functionalities provide reliable sites for derivatization, including etherification, acylation, and metal-catalyzed cross-coupling. The compound exhibits robust bench stability and is compatible with common protecting group strategies, facilitating its use in the synthesis of complex molecules and heterocyclic systems.

Synthesis

  • Route1
    • Vanillin, ≥97%|CS-1268660
      121-33-5
    • ~94%
    • In-stock
      2-Methoxyhydroquinone|CS-W014391
      824-46-4

    References

    • Fache, Maxence; Darroman, Emilie; Besse, Vincent; Auvergne, Remi; Caillol, Sylvain; Boutevin, Bernard Green Chemistry, 2014 , vol. 16, # 4 p. 1987 - 1998
  • Route2

    References

    • Lecea, B.; Aizpurua, J. M.; Palomo, C. Tetrahedron, 1985 , vol. 41, # 20 p. 4657 - 4666
  • Route3
    • null|null
      218903-28-7
    • ~24%
    • In-stock
      2-Methoxyhydroquinone|CS-W014391
      824-46-4
    • null|null
      218903-27-6

    References

    • Journal of Organic Chemistry, , vol. 63, # 24 p. 9139 - 9144

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   1.1064
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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