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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((bis(methylamino)methylene)amino)pentanoic acid

  • CAS No. 823780-66-1

  • Cat. No. CS-0100617
  • Molecule weight424.49
  • Purity≥98%
  • MDL No.MFCD15146390

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((bis(methylamino)methylene)amino)pentanoic acid|CS-0100617

Structure of 823780-66-1

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General Information

  • CAS No. 823780-66-1
  • Cat. No. CS-0100617
  • Purity ≥98%
  • MDL No. MFCD15146390
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₈N₄O₄
  • Molecular Weight 424.49
  • Synonym(s) (S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(2,3-dimethylguanidino)pentanoic acid
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC/N=C(NC)/NC

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((bis(methylamino)methylene)amino)pentanoic acid features a fluorenylmethyl carbamate (Fmoc) protecting group for amino-terminal stability and a bis(methylamino)methylene-substituted pentanoic acid side chain, enabling efficient incorporation into peptide synthesis workflows under standard conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((bis(methylamino)methylene)amino)pentanoic acid serves as a protected amino acid building block for peptide synthesis, enabling efficient incorporation of side-chain functionalized residues. The Fmoc group provides orthogonal protection with high stability and facile removal under mild basic conditions. The bis(methylamino)methylene-containing side chain facilitates selective transformations and acts as a versatile scaffold in the construction of heterocyclic systems and bioactive peptide analogs.

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   112.05
  • LogP   2.5533
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   8

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