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CS-W001157 4
Total: USD 88.00

2-Thiazolol

  • CAS No. 82358-07-4

  • Cat. No. CS-W019762
  • Purity≥95%
  • MDL No.MFCD02094166

*For research and further manufacturing use only, not for direct human use.

2-Thiazolol|CS-W019762

Structure of 82358-07-4

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General Information

  • CAS No. 82358-07-4
  • Cat. No. CS-W019762
  • Purity ≥95%
  • MDL No. MFCD02094166
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃NOS
  • Molecular Weight 101.13
  • Synonym(s) Thiazol-2-ol
  • SMILES OC1=NC=CS1

Description

2-Thiazolol is a heterocyclic compound featuring a five-membered ring with sulfur and nitrogen atoms, offering a unique electronic profile that enhances its utility in medicinal chemistry. This scaffold integrates readily into bioactive molecules due to its planar geometry and polar nature, enabling strong hydrogen bonding and dipole interactions. The compound demonstrates stability under standard bench conditions and serves as a key building block for pharmacologically active derivatives.

Application

2-Thiazolol serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling the construction of medicinally relevant scaffolds. Its reactive thiazole core facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, while its bench-stable nature supports reliable handling and purification. Functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   0.8487
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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