Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-4-methoxypyridine

  • CAS No. 82257-09-8

  • Cat. No. CS-W004248
  • Purity≥98%
  • MDL No.MFCD05664024

*For research and further manufacturing use only, not for direct human use.

3-Bromo-4-methoxypyridine|CS-W004248

Structure of 82257-09-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 82257-09-8
  • Cat. No. CS-W004248
  • Purity ≥98%
  • MDL No. MFCD05664024
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BrNO
  • Molecular Weight 188.02
  • Synonym(s) pyridine, 3-bromo-4-methoxy-
  • SMILES COc1ccncc1Br

Description

3-Bromo-4-methoxypyridine is a heterocyclic building block featuring a bromine at the 3-position and a methoxy group at the 4-position on the pyridine ring. This combination imparts enhanced reactivity in cross-coupling processes while maintaining stability under standard conditions. The electron-rich aromatic core facilitates palladium-catalyzed transformations, enabling efficient integration into pharmaceutical intermediates and functional materials.

Application

3-Bromo-4-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. The bromine substituent provides high reactivity under standard conditions, while the methoxy group enhances solubility and offers orthogonal functionalization potential. This compound exhibits excellent bench stability and is readily purified by flash chromatography, making it ideal for iterative synthesis of heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1

    References

    • Trecourt, Francois; Mallet, Marc; Mongin, Olivier; Gervais, Bruno; Queguiner, Guy Tetrahedron, 1993 , vol. 49, # 37 p. 8373 - 8380
  • Route2
    • In-stock
      3-Bromo-4-chloropyridine|CS-M3246
      36953-42-1
    • null|null
      124-41-4
    • ~76%
    • In-stock
      3-Bromo-4-methoxypyridine|CS-W004248
      82257-09-8

    References

    • Trecourt, Francois; Queguiner, Guy Journal of Chemical Research, Miniprint, 1982 , # 3 p. 912 - 942
  • Route3
    • null|null
      462-08-8
    • ~%
    • In-stock
      3-Bromo-4-methoxypyridine|CS-W004248
      82257-09-8

    References

    • Journal of Chemical Research, Miniprint, , # 3 p. 912 - 942

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   22.12
  • LogP   1.8527
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromo-4-methoxypyridine sigma3-Bromo-4-methoxypyridine manufacturer3-Bromo-4-methoxypyridine price3-Bromo-4-methoxypyridine structure3-Bromo-4-methoxypyridine SDSbuy 3-Bromo-4-methoxypyridine3-Bromo-4-methoxypyridine supplier3-Bromo-4-methoxypyridine uses3-Bromo-4-methoxypyridine molecular weightprice of 3-Bromo-4-methoxypyridine3-Bromo-4-methoxypyridine chemical name formula of 3-Bromo-4-methoxypyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label