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Structure of 821-48-7
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Bis(2-chloroethyl)amine hydrochloride is a bifunctional alkylating agent featuring two reactive chloroethyl groups. This compound facilitates efficient crosslinking of nucleophilic sites in biomolecules, enabling stable covalent conjugation in chemical biology and drug development applications. The hydrochloride salt enhances solubility and handling under standard conditions.
Bis(2-chloroethyl)amine (hydrochloride) serves as a versatile bifunctional electrophile in synthetic organic chemistry, enabling efficient crosslinking and cyclization reactions. Its two reactive chloroethyl groups facilitate rapid formation of nitrogen-containing heterocycles, including aziridines and larger ring systems, under mild conditions. The hydrochloride salt enhances shelf stability and solubility in aqueous/organic media, simplifying handling and purification. This reagent is particularly valuable in the synthesis of constrained scaffolds for medicinal chemistry and polymer science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H290-H302-H314
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Precautionary Statements : P234-P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P390-P405-P406-P501
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Lot numbers can be found on the outside label of a product: