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Structure of 820242-14-6
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N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(dimethylamino)cyclohexyl]urea features a sterically defined cyclohexyl amine scaffold paired with a highly electron-deficient aryl group, enabling robust hydrogen bonding and enhanced binding affinity in target-directed synthesis. This bench-stable urea integrates seamlessly into medicinal chemistry campaigns requiring polar, rigid scaffolds with improved metabolic resistance.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(dimethylamino)cyclohexyl]urea serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard urea coupling protocols. The trifluoromethyl groups confer enhanced metabolic stability and lipophilicity, while the chiral cyclohexylamine moiety provides a rigid scaffold for stereocontrolled interactions. Bench-stable and amenable to purification via standard chromatographic methods, it facilitates efficient synthesis of target molecules in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: