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Structure of 81779-27-3
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4-Hydroxy-1H-indole-3-carbaldehyde features a hydroxyl group at the 4-position and an aldehyde function at the 3-position of the indole core, enabling direct conjugation in C–C coupling reactions. The electron-rich aromatic system enhances reactivity in transition-metal-catalyzed transformations, while the carbonyl moiety serves as a key handle for derivatization. This scaffold supports rapid access to functionalized heterocycles in medicinal chemistry campaigns.
4-Hydroxy-1H-indole-3-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to indole-based scaffolds through standard coupling and functionalization reactions. Its ortho-hydroxyl and aldehyde groups offer complementary reactivity for late-stage derivatization, while demonstrating sufficient bench stability for routine handling in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: