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Structure of 81764-16-1
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4-Chloroquinolin-8-amine features a quinoline core with strategically positioned chlorine and amino groups, enabling direct incorporation into bioactive molecules. The electron-deficient heterocycle pairs effectively with transition metals in cross-coupling reactions, while the amine moiety offers a handle for derivatization. This compound serves as a key building block in medicinal chemistry and materials science.
4-Chloroquinolin-8-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into quinoline-based scaffolds via palladium-catalyzed cross-coupling reactions. The chloro group facilitates efficient functionalization at C4, while the primary amine at C8 supports derivatization through acylation, alkylation, or reductive amination. Bench-stable and compatible with standard purification methods, it functions reliably in the synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: