1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate

Name: 1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 81357-18-8
Cat. No. CS-W000565
Purity≥96%
MDL No.MFCD09842531

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate|CS-W000565

Structure of 81357-18-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate features a sterically hindered piperidine core with orthogonal carbonyl and ester functionalities, enabling selective transformations in complex molecular architectures. The tert-butyl and methyl groups enhance stability and solubility under standard conditions, while the 4-oxo group provides a reactive handle for reductive amination and cyclization reactions.

Application

1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted piperidine scaffolds. The molecule combines a stable tert-butyl ester, a methyl-substituted nitrogen, and a ketone functionality, offering orthogonal reactivity for selective transformations. Its bench-stable nature and compatibility with standard coupling and reduction protocols facilitate streamlined synthesis of complex heterocycles and bioactive molecules.

General Information

CAS No. 81357-18-8
Cat. No. CS-W000565
Purity ≥96%
MDL No. MFCD09842531
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₉NO₅
Molecular Weight 257.28
Synonym(s) None
SMILES O=C(N1C(C(OC)=O)CC(CC1)=O)OC(C)(C)C

Computational Chemistry Data

TPSA 72.91
LogP 1.128
H_Acceptors 5
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

81357-18-8 sigma81357-18-8 manufacturer81357-18-8 price81357-18-8 structure81357-18-8 SDSbuy 81357-18-881357-18-8 supplier81357-18-8 uses81357-18-8 molecular weightprice of 81357-18-881357-18-8 chemical name formula of 81357-18-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-tert-Butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate

CAS No. 81357-18-8

Recommended Products