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Structure of 813-72-9
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2,2-Dimethylhexanoic acid features a sterically hindered aliphatic chain terminating in a carboxylic acid group. This structural motif enhances metabolic stability and resistance to enzymatic degradation, making it valuable for bioactive molecule design. The geminal dimethyl substitution reduces chain flexibility and influences partitioning behavior in lipophilic systems.
2,2-Dimethylhexanoic acid serves as a stable, bench-friendly building block for the synthesis of bioactive esters and amides, leveraging its sterically hindered α-carbon to resist racemization during coupling. Its hydrophobic aliphatic chain enhances membrane permeability in peptidomimetic architectures, while the carboxylic acid functionality enables straightforward derivatization via standard amidation or esterification protocols.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: