Methyl 4-bromo-1H-pyrazole-3-carboxylate

Name: Methyl 4-bromo-1H-pyrazole-3-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 81190-89-8
Cat. No. CS-W019707
Purity≥96%
MDL No.MFCD00466326

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-bromo-1H-pyrazole-3-carboxylate|CS-W019707

Structure of 81190-89-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 81190-89-8
Cat. No. CS-W019707
Purity ≥96%
MDL No. MFCD00466326
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅BrN₂O₂
Molecular Weight 205.01
Synonym(s) 1H-Pyrazole-3-carboxylicacid, 4-bromo-, methyl ester
SMILES O=C(C1=NNC=C1Br)OC

Description

Methyl 4-bromo-1H-pyrazole-3-carboxylate features a brominated pyrazole core with a methyl ester group, enabling direct incorporation into Suzuki-Miyaura and other cross-coupling reactions. The electron-deficient pyrazole ring enhances reactivity, while the bench-stable ester facilitates handling and purification under standard conditions.

Application

Methyl 4-bromo-1H-pyrazole-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyrazole scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates reliable functionalization under standard Suzuki, Stille, or Negishi conditions, while the ester moiety offers compatibility with reduction, hydrolysis, and further derivatization. Its bench-stable nature and straightforward purification make it well-suited for iterative medicinal chemistry campaigns and process-scale applications.

Synthesis

Route1
- 190263-45-7
- ~72%
- In-stock
  
  81190-89-8
References
- Erion, Mark D.; Rydzewski, Robert M. Nucleosides and Nucleotides, 1997 , vol. 16, # 3 p. 315 - 337

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 54.98
LogP 0.9588
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

Methyl 4-bromo-1H-pyrazole-3-carboxylate sigmaMethyl 4-bromo-1H-pyrazole-3-carboxylate manufacturerMethyl 4-bromo-1H-pyrazole-3-carboxylate priceMethyl 4-bromo-1H-pyrazole-3-carboxylate structureMethyl 4-bromo-1H-pyrazole-3-carboxylate SDSbuy Methyl 4-bromo-1H-pyrazole-3-carboxylateMethyl 4-bromo-1H-pyrazole-3-carboxylate supplierMethyl 4-bromo-1H-pyrazole-3-carboxylate usesMethyl 4-bromo-1H-pyrazole-3-carboxylate molecular weightprice of Methyl 4-bromo-1H-pyrazole-3-carboxylateMethyl 4-bromo-1H-pyrazole-3-carboxylate chemical name formula of Methyl 4-bromo-1H-pyrazole-3-carboxylate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-bromo-1H-pyrazole-3-carboxylate

CAS No. 81190-89-8

Recommended Products