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Structure of 124668-49-1
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N,N-Dimethylazetidin-3-amine dihydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a strained four-membered ring with two methyl groups on nitrogen. This polar, protonated form enhances solubility in aqueous and polar organic media, enabling efficient incorporation into synthetic intermediates. The tertiary amine moiety facilitates nucleophilic reactivity in coupling reactions and functionalization processes.
N,N-Dimethylazetidin-3-amine dihydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient synthesis of bioactive heterocycles. Its tertiary amine functionality offers excellent solubility and nucleophilicity, facilitating rapid conjugation in amide couplings and reductive amination protocols. The azetidine core provides enhanced metabolic stability and improved pharmacokinetic profiles in drug candidates. Bench-stable and easily handled, it functions reliably in standard reaction workflows, supporting scalable synthesis of targeted API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: