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CS-W001157 4
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Methyl 2-((diphenylmethylene)amino)acetate

  • CAS No. 81167-39-7

  • Cat. No. CS-W018831
  • Purity≥97%
  • MDL No.MFCD06661218

*For research and further manufacturing use only, not for direct human use.

Methyl 2-((diphenylmethylene)amino)acetate|CS-W018831

Structure of 81167-39-7

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General Information

  • CAS No. 81167-39-7
  • Cat. No. CS-W018831
  • Purity ≥97%
  • MDL No. MFCD06661218
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₅NO₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(OC)C/N=C(C1=CC=CC=C1)\C2=CC=CC=C2

Description

Methyl 2-((diphenylmethylene)amino)acetate features a diphenylmethylene-amino moiety that confers enhanced stability and solubility in organic media. This compound integrates readily into multistep synthesis workflows, serving as a key intermediate for heterocyclic scaffolds and functionalized amine derivatives under standard conditions.

Application

Methyl 2-((diphenylmethylene)amino)acetate serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds through controlled imine formation and subsequent cyclization. Its diphenylmethylene-imino functionality offers enhanced stability and facilitates selective transformations under mild conditions. The molecule exhibits good bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step syntheses.

Synthesis

  • Route1

    References

    • TARGACEPT, INC. Patent: WO2006/23630 A2, 2006 ; Location in patent: Page/Page column 39-40; 65 ;
  • Route2

    References

    • WO2010/123792 A1, ; Page/Page column 11-13 ;
  • Route3
    • null|null
      1816-92-8
    • Diphenylmethanethione|CS-1142168
      1450-31-3
    • ~61%
    • In-stock
      Methyl 2-((diphenylmethylene)amino)acetate|CS-W018831
      81167-39-7

    References

    • Mloston; Romanski; Linden; Heimgartner Polish Journal of Chemistry, 1996 , vol. 70, # 7 p. 880 - 890

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.66
  • LogP   2.697
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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