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Structure of 81115-63-1
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4-Amino-1H-indazole-5-carboxylic acid features a fused bicyclic core with complementary electron-rich and acidic functionalities. The para-amino group enhances nucleophilicity, while the carboxylic acid enables direct conjugation or salt formation. This scaffold integrates readily into bioactive molecules requiring hydrogen bonding capacity and metabolic stability under standard conditions.
4-Amino-1H-indazole-5-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient access to indazole-based scaffolds prevalent in medicinal chemistry. The molecule combines an electron-rich amine with a carboxylic acid for direct derivatization via amidation, esterification, or coupling reactions. Its stability under standard bench conditions and compatibility with diverse functional groups support reliable use in multi-step syntheses, including the construction of kinase inhibitors and other targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: