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CS-W001157 4
Total: USD 88.00

(4,4-Difluorocyclohexyl)methanamine hydrochloride

  • CAS No. 809273-65-2

  • Cat. No. CS-0053216
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4,4-Difluorocyclohexyl)methanamine hydrochloride|CS-0053216

Structure of 809273-65-2

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General Information

  • CAS No. 809273-65-2
  • Cat. No. CS-0053216
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClF₂N
  • Molecular Weight 185.64
  • Synonym(s) 1-(Aminomethyl)-4,4-difluorocyclohexane Hydrochloride
  • SMILES Cl.NCC1CCC(F)(F)CC1

Description

This bench-stable amine features a difluorocyclohexyl scaffold that imparts enhanced metabolic stability and lipophilicity. The hydrochloride salt form ensures excellent solubility in aqueous systems, facilitating use in synthetic workflows requiring polar media. Ideal for incorporating into bioactive molecules where fluorinated cyclohexyl motifs are desired.

Application

(4,4-Difluorocyclohexyl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability due to the geminal difluoro substitution. Its amine functionality enables straightforward derivatization via alkylation, acylation, or reductive amination, while the hydrochloride salt form ensures excellent bench stability, solubility, and ease of handling in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.1924
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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