Lot numbers can be found on the outside label of a product:
4-Iodo-3,5-dimethylphenol
-
CAS No. 80826-86-4
- Cat. No. CS-M3254
- Purity≥95%
- MDL No.MFCD00174284
*For research and further manufacturing use only, not for direct human use.
Structure of 80826-86-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 80826-86-4
- Cat. No. CS-M3254
- Purity ≥95%
- MDL No. MFCD00174284
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₉IO
- Molecular Weight 248.06
- Synonym(s) 3,5-Dimethyl-4-iodophenol; 4-Iodo-3,5-dimethylphenol; 2-Jod-5-hydroxy-m-xylol
- SMILES OC1=CC(C)=C(I)C(C)=C1
Description
4-Iodo-3,5-dimethylphenol offers a sterically hindered phenolic scaffold with iodine at the para position relative to the hydroxyl group. The dimethyl substituents enhance electron density and stability, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. This bench-stable reagent integrates readily into complex molecular architectures requiring controlled functionalization.
Application
4-Iodo-3,5-dimethylphenol serves as a versatile building block in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions. The iodine substituent enables efficient coupling under mild conditions, while the ortho-methyl groups provide steric and electronic stabilization. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures, including bioactive heterocycles and pharmaceutical intermediates.
Synthesis
-
Route1
-
108-68-9 - ~77%
-
In-stock
80826-86-4
References
-
Lu, Yixin; Weltrowska, Grazyna; Lemieux, Carole; Chung, Nga N.; Schiller, Peter W. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 3 p. 323 - 325 Title/Abstract Full Text View citing articles Show Details Lu; Schiller Synthesis, 2001 , # 11 p. 1639 - 1644
-
-
Route2
-
108-68-9
- ~54%
-
In-stock
24242-79-3 -
In-stock
80826-86-4
References
-
Tetrahedron Letters, , vol. 51, # 16 p. 2170 - 2173
-
-
Route3
-
108-68-9
- ~%
-
7282-03-3
-
In-stock
80826-86-4
References
-
Angewandte Chemie, , vol. 52, p. 263,265
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 20.23
- LogP 2.61364
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-Iodo-3,5-dimethylphenol sigma4-Iodo-3,5-dimethylphenol manufacturer4-Iodo-3,5-dimethylphenol price4-Iodo-3,5-dimethylphenol structure4-Iodo-3,5-dimethylphenol SDSbuy 4-Iodo-3,5-dimethylphenol4-Iodo-3,5-dimethylphenol supplier4-Iodo-3,5-dimethylphenol uses4-Iodo-3,5-dimethylphenol molecular weightprice of 4-Iodo-3,5-dimethylphenol4-Iodo-3,5-dimethylphenol chemical name formula of 4-Iodo-3,5-dimethylphenol