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Structure of 801315-74-2
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tert-Butyl 4-amino-1H-indazole-1-carboxylate features a bench-stable indazole core with a strategically positioned amino group enabling direct functionalization. The tert-butyl ester facilitates protection and subsequent cleavage under mild acidic conditions, streamlining access to the free carboxylic acid. This derivative integrates readily into synthetic routes for bioactive heterocycles.
tert-Butyl 4-amino-1H-indazole-1-carboxylate serves as a versatile building block for indazole-based pharmaceutical scaffolds, enabling direct functionalization at the 4-amino position. The tert-butyl carbamate group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. It functions effectively in palladium-catalyzed cross-coupling reactions and supports efficient derivatization in medicinal chemistry campaigns targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: