Boc-D-Phe(4-Me)-OH

Name: Boc-D-Phe(4-Me)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 80102-27-8
Cat. No. CS-0153094
Purity≥98%
MDL No.MFCD01317726

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 80102-27-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 80102-27-8
Cat. No. CS-0153094
Purity ≥98%
MDL No. MFCD01317726
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₁NO₄
Molecular Weight 279.33
Synonym(s) Boc-D-4-Methylphenylalanine
SMILES CC1=CC=C(C[C@@H](NC(OC(C)(C)C)=O)C(O)=O)C=C1

Description

Boc-D-Phe(4-Me)-OH features a para-methyl-substituted phenylalanine scaffold with a tert-butoxycarbonyl (Boc) protecting group, enabling straightforward incorporation into peptide sequences. The methylated aromatic ring enhances lipophilicity and metabolic stability, while the Boc moiety ensures compatibility with standard Fmoc-based solid-phase synthesis protocols. This derivative serves as a key building block for bioactive peptide analogs requiring D-amino acid substitution and side-chain hydrophobicity.

Application

Boc-D-Phe(4-Me)-OH serves as a valuable chiral building block for the synthesis of D-peptide analogs and bioactive oligomers. The 4-methyl substituent enhances metabolic stability and conformational rigidity, while the Boc group provides reliable protection for amine-directed coupling reactions. This derivative exhibits excellent bench stability, compatibility with standard peptide coupling protocols, and facilitates efficient purification via common chromatographic methods.

Synthesis

Route1
- 178413-84-8
- ~%
- In-stock
  
  80102-27-8
References
- Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 19 p. 5607 - 5612

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 75.63
LogP 2.51542
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 4

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

Boc-D-Phe(4-Me)-OH sigmaBoc-D-Phe(4-Me)-OH manufacturerBoc-D-Phe(4-Me)-OH priceBoc-D-Phe(4-Me)-OH structureBoc-D-Phe(4-Me)-OH SDSbuy Boc-D-Phe(4-Me)-OHBoc-D-Phe(4-Me)-OH supplierBoc-D-Phe(4-Me)-OH usesBoc-D-Phe(4-Me)-OH molecular weightprice of Boc-D-Phe(4-Me)-OHBoc-D-Phe(4-Me)-OH chemical name formula of Boc-D-Phe(4-Me)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Boc-D-Phe(4-Me)-OH

CAS No. 80102-27-8

Recommended Products